What are SARMS?

SARMs are different from anabolic steroids. SARMs and anabolic steroids are interchangeable.
SARMs are safe. SARMs can damage organs.
SARMs work like a charm. SARMs are not worth the hype.

And the list goes on.

Information on what SARMs are seem to be a cloud of confusion. It has been in around in the last 40 years yet we feel hindered to discuss it.

In this article, we will dispel the uncertainties surrounding this compound.

SARMs stands for Selective Androgen Receptor Modulators. Before going to what SARMs are, let’s take these terms by the piece.

Androgens are a group of hormones responsible for male traits and reproductive activity. They are present in both men and women, having testosterone and androstenedione as the primary androgen, respectively. It is usually associated only with men although women’s bodies also produce and utilize them in over 200 actions. One of the main purposes of androgens in women is to be converted to estrogens. Dihydrotestosterone (DHT), dehydroepiandrosterone (DHEA), and DHEA sulfate (DHEA-S) are other androgens.

Androgen receptors (ARs) are located inside the cells that make up the reproductive tissues, brain, spinal cord, and other parts of the body. They function primarily in the expression of reproductive and aggressive behaviors. Androgens such as testosterone bind to androgen receptors and produce reproductive-related responses.

Then there are androgen receptor modulators. Biological conditions such as hyperthermia, aging, and chronic infections, industrial chemicals, tobacco, alcohol, and pharmacological drugs such as steroids and SARMs are AR modulators. They interfere with androgens resulting in interrupted binding with the receptors, consequently disturbing physiological responses.

SARMs and Anabolic Steroids Defined

Anabolic steroids or more properly called anabolic-androgenic steroids (AAS) compete with endogenous androgens in attaching to receptors. Having a similar structure to testosterone, AAS may produce varying androgenic traits such as increased protein synthesis in skeletal muscles, growth of facial and body hair, acne, aggression, and other related characteristics.

In general, AAS impact all cell-containing androgen receptors leading to changes even where they are not warranted. Long-term and excessive use of anabolic steroids may result in abnormal lipids, hypertension, and liver damage.

SARMs are called selective because unlike steroids, they do not attach to every androgen receptors in the body. They are tissue-selective — they have a special affinity to the muscle and bone tissues where the concentration of their effects are observed.